Diagnosis and monitoring a case of light-chain deposition disease in the kidney using a new, sensitive immunoassay.

نویسندگان

  • Ian Brockhurst
  • Kevin P G Harris
  • Claire S Chapman
چکیده

A 59-year-old male was diagnosed with nephrotic syndrome secondary to light-chain deposition disease. There was no other evidence of a B cell clonal disorder or amyloidosis; circulating free light chains were identified using a new immunoassay (Freelite) and used to monitor disease progression. Improvement in renal function and proteinuria following VAMP chemotherapy correlated with a reduction in circulating light-chain levels. This case demonstrates a new tool in monitoring light-chain deposition disease in the kidney.

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عنوان ژورنال:
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

دوره 20 6  شماره 

صفحات  -

تاریخ انتشار 2005